Double-blind randomized clinical and laboratory research projects with placebo control designed to the most exacting scientific standards in support of the ever widening fields of application of Sensolite are on the go under statutory licenses. These investigations sponsored and financed by Sensolite are carried out by university institutes and research partners of international renown.
Our research is aimed at the exploration of biophysical, gene expression1 and biological background processes that confirm, expose and verify the
a. clinical experiences of whole-body surround treatment with polarized light;
b. results of scientific research carried out earlier by Márta Fenyő, inventor;
c. thirty years of clinical experience in the use of various appliances designed for local treatment with polarized light, and
d. other scientific publications on the effects of treatment with polarized light.
VERIFICATION OF THE POSITIVE IMPACTS OF WHOLE-BODY SURROUND TREATMENT WITH POLARIZED LIGHT ON THE PHYSICAL PERFORMANCE BY THE USE OF METHODS OF MOLECULAR BIOLOGY
This issue is of particular substance for sportsmen and people actively involved in sports. In addition to the clinical experiences the results of earlier research projects of relevance prove that polarized light stabilizes the cell membrane of erythrocytes and boosts their ability to bind and deliver oxygen. The surplus oxygen is delivered through circulation to all organs and cells of the human body.
Our aim is to confirm – by the use of state-of-the-art scientific means available in the fields of immunology, genomics1 and FACS2 – our results supported by ample experiences and best research methods available earlier. We measure the impact of whole-body surround treatment by polarized light on mediators: on key parameters in immunology and inflammatory response.
In healthy persons in order to exclude inflammatory reactions following Sensolite whole body polarized light treatment we detected, among others, the changes in the CRP3 level. The lack of any changes in CRP and immunoglobulin levels suggest that polarized light did not provoke inflammatory changes.
GENOMIC RESEARCH FOR THE INVESTIGATION OF THE IMMUNE RESPONSE OF THE HUMAN ORGANISM BASED ON THE MEASUREMENT OF THE GENE EXPRESSION OF LYMPHOCYTES USING THE GWAS (GENOME-WIDE-ASSOCIATION STUDY)APPROACH
When the changes in the gene expression pattern of lymphocytes of allergic children treated regularly in the Sensolite beds by polarized light were measured, as a consequence a strong anti-inflammatory response was detected. The primary gene expression results at full genome level showed the significant and reproducible reduction of the gene expression of chemokines responsible for the local recruitment of inflammatory cells. Moreover, the increase of a leukotrene catabolysing enzyme (CYP4F2) gene expression suggests a marked anti-inflammatory effect, as well. Accordingly, considerable amendments to previous clinical indications are feasible for a number of diseases characterized by chronic inflammation.
This research project is underway at the designated and accredited laboratory of the Department for Genetics, Celland Immunobiology of the Semmelweis University, under the leadership of Prof. Dr. András Falus. The clinical studies of allergic children are performed by Dr. Anna Madarasi PhD., chief physician in the Szent János Hospital of the Metropolitan Municipality and the Unified Hospitals of North Buda.
INVESTIGATION OF THE EFFECT OF POST-OPERATIONAL POLARIZED LIGHT THERAPY AFTER THE SURGICAL TREATMENT OF CERTAIN SPINE DISEASES AND ALSO IN THE CONSERVATIVE TREATMENT OF SPINE DISEASES ACCOMPANIED BY PAIN SYNDROME
The aim of this research project is to investigate the effect of whole-body Sensolite therapy by polarized light on the time to healing of post-operative wounds arising from the surgical treatment of certain spine diseases and the related change in the function of the musculature around the area of surgical intervention, including the wound pain and the change in the psychological condition caused by the relieving of pain. This research is carried out under the leadership of Dr. Péter Pál Varga, Head Surgeon and Director, at the National Centre for Spinal Disorders. In addition to the fundamental investigations, we are making efforts at the Institute for Genetic, Cellular and Immune Biology of the Semmelweis University of Medical Science to obtain quantifiable results regarding the genomic background of the stimulation of wound healing by polarized light, using the GWAS5 approach in the simultaneous investigation of all human gene expression patterns.
EFFECT OF TREATMENT WITH POLARIZED LIGHT IN VIVO ON THE TUMOROUS DISORDERS OF INFANCY
At Paediatric Clinic No 2 of the Semmelweis Medical University investigations led by Dr. Miklós Garami, Associate Professor, are in progress concerning the adjunctive effect of polarized light on children suffering from brain tumour, used exclusively in the periods between the cycles of chemotherapy as an adjuvant to the currently recognized and generally applied protocol in oncological treatments. Our aim is to investigate the response of children to the polarized light manifesting in their general condition. The objective of the clinical investigation is to demonstrate the improvement of physical and psychological condition of children treated in this manner, compared to the control group, thus making chemotherapy even more efficacious.
We intend to carry out the in-depth investigation of changes in immunity in vivo, on-going monitoring of the status of the tumour using imaging processes, covering also the immunological processes detectable in the haemogram and changes in the metabolism. The changes in the quality of life are recorded by the use of adequate test methods. At the Institute for Genetic, Cellular and Immune Biology of the Semmelweis University of Medical Science Prof. Dr. András Falus and his team carry out, using genomic and FACS tests, the investigation of changes in structure and gene expression induced by polarized light in T-lymphocytes6 revealed in the background of clinical experiences.
EFFECT OF WHOLE BODY SURROUND THERAPY BY POLARIZED LIGHT ON THE TENDENCY TO HEALING OF BONE FRACTURES, ON THE QUALITY OF CICATRISATION AND THE SPEED OF OSSIFICATION
Using daily treatments with polarized and non-polarized light randomized double-blind tests carried out under placebo controlled conditions are used for comparing the tendency to healing and the time to healing of bone fractures. These investigations are carried out by Prof. Dr. László Hangody, Head of Department, Department of Orthopaedics at the Uzsoki Hospital, Chairman of the Board of Orthopaedic Surgeons.
Relying on the ever increasing number of patients of the nationwide network of Sensolite health parlours and supported by the common IT infrastructure, data on patients are collected in a standard format for scientific and statistical purposes. Having read the information brochure on the survey and signed it for approval the patients assign scores on a subjective scale to the questions of the survey that cover the key complaints. Data are recorded at the commencement of the treatment and later, at various stages during the therapy, and also at the end of it.
1 Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product
2 Genomics is the joint determination of the structure (variants) and functions (gene expression) of the genomes of organisms.
3 FACS: Immune phenotyping, citofluorimetry ily at the level of the messenger RNS (mRNS).
4 CRP: C-reactive protein
5 GWAS: Genome-wide associations study
6 T-lymphocyte: A class of lymphocytes responsible for cell-mediated immunity and a number of effects of immune control.